Eight hundred civilians - including at least 177 children - have been killed since Russia-backed regime forces launched an assault on the besieged enclave outside Damascus on Feb 18, the Syrian Observatory for Human Rights said in its latest death toll.
The grim conclusions, based on more than 500 interviews, coincided with reports of heavy civilian casualties in the Damascus suburb of eastern Ghouta, where Syrian and Russian forces pushed on with a ferocious offensive aimed at crushing the last major rebel stronghold in the area.
Russian Federation pledged to let the insurgents and their families leave Eastern Ghouta, but rebels have been sceptical of the offer from Moscow, a key ally of Syrian President Bashar al-Assad.
The ministry says its negotiators in Syria late on Monday called on all rebels leaders in eastern Ghouta to allow civilians leave the area, which has been under a crippling siege for weeks.
He says that "nearly half of the food carried on the convoy" could not be delivered.
The Assad regime, backed by Russian Federation, claims that it is only targeting "members of banned terrorist groups who are unprotected by the truce", as Reuters puts it.
"The situation is catastrophic", said a doctor speaking from the rebel pocket.
Though they are war crimes investigators, the statement notes they are not a tribunal empowered to take the investigations any further.
Syrian Kurdish media say at least 13 civilians were killed in Turkish shelling on the town of Jindaris, as Turkish forces try to press their advances on the Kurdish-held Afrin enclave in northwest Syria.
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The Russian mission to the United Nations in Geneva did not immediately respond to the findings.
In Hammuriyeh, air strikes were continuing to pummel the town on Tuesday.
After the implementation of the five-hour daily humanitarian pauses, Damascus tried to send dozens of trucks with aid to Eastern Ghouta, but the attempts were thwarted by the continuing shelling of the humanitarian corridor by jihadist groups.
International Committee of the Red Cross (ICRC) convoy seen crossing into eastern Ghouta near Wafideen camp in Damascus, March 5, 2018.
Iyad Abdelaziz, a member of the Douma Local Council, said nine aid trucks had to leave the area after government shelling and airstrikes intensified in the evening.
More than 340,000 people have been killed and millions displaced in Syria since the start of the civil war in 2011 with the brutal repression of anti-government protests.
Netherlands U.N. Ambassador Karel van Oosterom was speaking after the Council was briefed behind closed doors on the situation in Syria at the request of Britain and France. "The people sit with multiple families, with thousands of families in basement shelters", he said. The goal of the operation is clear Turkey's Syrian border from the terrorist threat.
Government troops have advanced rapidly across farmland in Eastern Ghouta in the past week and have wrested control of more than 40 percent of the territory.