Also on Friday, Slovak authorities started evacuating people in the town of Sturovo, near the southern border with Hungary after four World War II bombs were found, according to The Associated Press.
The bomb was defused by a team of five police specialists, and it was transported to an area outside of town before being destroyed in a controlled explosion.
The area to be cleared includes Berlin Hauptbahnhof - the central railway station, an army hospital, the economy and transport ministries and the embassies of Indonesia and Uzbekistan, the BBC quoted the German police as saying.
It was found last Wednesday during construction work in Heidestrasse.
Previous year some 60,000 people were evacuated from their homes in Frankfurt after a massive bomb dropped by Britain's Royal Air Force was unearthed.
Temporary shelters were set up for those affected by the evacuation.
The discovery had caused widescale disruption to the German capital.
Experts were able within a short space of time to remove the fuse from the bomb and make it safe, a police spokesman said on Friday.
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An estimated more than 2,000 tons of bombs and ammunition are unearthed in Germany each year.
TRT World 's Ira Spitzer reports from Berlin.
British bombers alone dropped more than 45,000 tons of bombs during the conflict.
They have also been discovered in other European cities.
IN the end, it took several hours.
Images showed the central train station to be completely deserted of passengers while the operation to remove the bomb was carried out.
A dismantled World War Two bomb is transported at a construction site next to the central train station in Berlin, Germany, April 20, 2018.