Ghanen said she always told her son, who was the founder of the al-Qaeda terrorist organisation, to stay away from bad gangs but that he never admitted his activities to her because he (Osama) loved her so much.
In an interview with Guardian, Ghamen said; "My life was very hard because he was so far away from me".
'She loved him so much and refuses to blame him.
Ghanem, who lives in a mansion in a wealthy area of Jeddah, said he was a deeply religious individual who "changed" at university.
"The people at university changed him". Ms Ghanem told the newspaper, when asked how she felt after learning her son had become a jihadist militant.
In an interview to British newspaper the Guardian, she remembered her son as "shy and good child growing up", who was "brainwashed" at university. "They got money for their cause", Ghanem said. "I did not want any of this to happen", she said. "Why would he throw it all away like that?" she says.
Living sheltered lives as a prominent but controversial family in their native Saudi Arabia, several of the family members opened up about bin Laden's childhood and his eventual transformation into one of the most notorious figures in recent history.
The terrorist leader was shot dead by a US Navy Seal team in Pakistan in 2011 and his son, Hamza, who jihadis have hailed as the "heir" to the leadership of al-Qaeda, past year called on Muslims around the world to launch revenge terror attacks on the US, reports the MailOnline.
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Ghanem and her family live in a well-to-do section of Jeddah, a testament to the fact that the bin Laden construction business is one of the largest in the Middle East.
He was killed on May 1, 2011 when U.S. Navy SEALs raided his compound in Abbottabad, Pakistan.
"Then the next thing I knew, Hamza was saying "I'm going to avenge my father".
"It has been 17 years now [since 9/11] and she remains in denial about Osama". Instead, she blames those around him.
After notoriously eluding US forces for almost a decade after the September 11 attacks, bin Laden was killed by Navy SEALs in a raid on his Pakistan hideout seven years ago. Think twice about what you are doing. She only knows the good boy side, the side we all saw. "You are entering disgusting parts of your soul.'" said Hassan in a visible gesture of not being aligned with the heir of OBL. Our family overseas all came back to Saudi, ' decried Ahmad.
The Guardian also spoke with top intelligence officials, who described Bin Laden's motivation as he tried to create a war between the West and Islam.