McCain made a decision to stop treatment for the brain cancer he had been battling for over a year, his family announced on Friday, precipitating a rare moment of bipartisan empathy for the Vietnam war hero.
Pence, in a tweet on McCain's death, said: "Karen and I send our deepest condolences to Cindy and the entire McCain family on the passing of Senator John McCain". He lost to Barack Obama, who, along with George W. Bush, will reportedly eulogize McCain at his funeral, which has been planned for the past year.
In 1967, his aircraft was shot down during a bombing mission over Vietnam, where he was held as a prisoner of war for five and a half years.
Back in the Senate, McCain heard the call of war again, as American foreign policy was transformed after the September 11, 2001, terror attacks, and he became a forceful proponent of the USA use of force overseas.
After McCain's announcement on Friday, Ducey lauded the ailing senator as an "American hero" who has always put the country before himself.
Former vice-president Joe Biden, who developed a friendship with McCain while they served together in the Senate, said the Arizona lawmaker will "cast a long shadow".
U.S. Sen. Lindsey Graham, a close friend, said: "America and Freedom have lost one her greatest champions". McCain was the unsuccessful Republican candidate for the 2008 presidential election and was an active voice in US foreign policy debate, as Chairman of the Senate Armed Services Committee from January 2015 until his death.
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Farrell, head of the Vatican office for laity and family and former auxiliary bishop of Washington, D.C., and Cardinal Sean P. Cupich, who said he heard about the letter Sunday morning after returning from Ireland , said he fully supports the pope.
Elsewhere on Twitter, McCain's trying years in the military were noted among commemorators as a defining feature of the Vietnam War veteran's life.
Talk show hosts Jimmy Kimmel and Ellen DeGeneres paid tribute and shared memories of their experiences with the Arizona Senator while Stephen King and Ron Perlman took the time to honor the war hero and take jabs at Trump.
"It's one of the most important moments of McCain's career".
The governor has so far remained silent on who he has in mind out of respect for McCain and his family.
Meghan continued "all that I am is thanks to him".
Senate Majority leader Addison Mitchell McConnell described Senator McCain's life as a "bright example" in a world filled with cynicism about national unity.