Weather Underground meteorology director Jeff Masters said Florence eventually could strike as merely a Category 1 hurricane with winds less than 100 miles per hour (160 kph), but that's still enough to cause at least $1 billion in damage.
No storm watches or warnings are in effect for Georgia.
Shepard Smith and Flaherty said reports showed storm surge from the system is likely to be felt dozens of miles inland, including along the Neuse River Basin - which stretches inward from New Bern toward Rocky Mount and Nashville, N.C. The order eases regulations on trucks hauling gasoline and relief supplies into Georgia. Experts are saying Florence, a "monster", could be one of the most powerful storms to ever hit the East Coast.
Hoffman, along with Billy Sample and Sample's wife, say they've got homes to keep an eye on and pets to worry about.
Sand bags surround homes on North Topsail Beach, N.C., September 12, 2018, as Hurricane Florence threatens the coast.
It's a horrifying spectacle to behold, and the hurricane hasn't even struck land yet.
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Mr Cooper's warnings were echoed by his SC counterpart, Henry McMaster, who stated that emergency services may not be able to reach residents if they remain in areas where evacuation orders have been issued.
Millions of people on the East Coast of the United States find themselves in the path of a monster Category 4 hurricane that threatens catastrophic coastal flooding and damage in the billions of U.S. dollars.
"Now is the time to shelter from life-threatening wind", the agency added.
The storm was heading for the coast of North and SC but heavy rain was also expected in Virginia to the north and Georgia to the south.
More than 1 million residents have been ordered to evacuate the coastline of the three states, while university campuses, schools and factories were being shuttered.
"We've made a decision to stay and it's on us", he said. All interests from SC into the mid-Atlantic region should complete preparations and follow any advice given by local officials.
TRT World's Nicole Johnston is on the coast in Wilmington, North Carolina, where people are preparing for the worst.
As of 11 a.m., the potentially catastrophic Category 4 storm was centered 485 miles (785 kilometers) southeast of Wilmington, moving at 15 mph (24 kph) with winds of 130 mph (215 kph) and enough moisture to dump feet of rain on the region.