Many worldwide observers were alarmed by Meng's election as president of Interpol in 2016, worrying that he might shift the global policing organization's focus and resources over to investigations favored by Beijing, such as hunting down political dissidents or outspoken tycoons who had fled China.
The French ministry said last Friday that Mr Meng's family had not heard from him since Sept 25, and French authorities said his wife was under police protection after getting threats.
Ms Meng said her husband had traveled back to China for work, after a visit to the Nordics, saying: "His job is very busy.we connected every day".
Meng's wife told reporters in the French city of Lyon on Sunday she hasn't heard from her husband since September 25.
She also said that she was scared for his life after she received a text message on her phone with a knife emoji on September 25.
Soon after the CCDI made public Meng's status, Grace Meng, who first learned about the development from the AP, said she was struggling to believe what it said.
But the call never came, she said, adding that she did not what happened to her husband.
Mr Meng's unexplained disappearance in China late last month, which had prompted the French Government and Interpol to make their concerns known publicly, has threatened to tarnish Beijing's image.
The first Chinese national to lead Interpol, his election caused controversy at the time, especially among human rights activists.
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Reports from April said Mr Meng had been relieved of his position as a member of the party committee at the Ministry of Public Security, with no explanation given.
China's National Supervisory Commission announced just before midnight that Meng had been detained while an unspecified law violation was being investigated.
Mr Xi has been seeking the return of officials and business people accused of fraud and corruption from overseas, sometimes with the help of Interpol in an arrangement human rights advocates say is prone to abuse.
There have been several cases in recent years of senior Chinese officials vanishing without explanation, only for the government to announce weeks or even months later that they have been put under investigation, often for suspected corruption.
Meng's wife has said her husband sent her an image of a knife before he disappeared. He was elected president of Interpol in 2016 and was due to serve until 2020, according to the organization's website. "For the husband whom I deeply love, for my young children, for the people of my motherland, for all the wives and children, so that their husbands and fathers will no longer disappear".
It was unclear how Meng could have fallen foul of the Chinese authorities.
President Xi has also placed a premium on obtaining the return of officials accused of fraud and corruption from overseas.